Coinbase Research Chief David Duong: Macro and Institutional Flows Could Send BTC, ETH Vertical — Key Trading Catalysts to Watch

According to @MilkRoadDaily, Coinbase Head of Research David Duong says macro conditions and rising institutional participation are the primary catalysts that could drive crypto markets sharply higher, urging traders to tune in for details. Source: https://twitter.com/MilkRoadDaily/status/1969198449317793831 Traders can monitor U.S. CPI trends and FOMC policy signals for risk-asset direction, and track spot Bitcoin ETF net flows as a proxy for institutional demand. Sources: https://www.bls.gov/cpi/ https://www.federalreserve.gov/monetarypolicy.htm https://www.farside.co.uk/bitcoin-etf-flows/
SourceAnalysis
In a recent statement that has captured the attention of cryptocurrency traders worldwide, the Head of Research at Coinbase has highlighted how macroeconomic factors combined with institutional involvement could propel the crypto market to new heights. According to Milk Road Daily, this insight comes from David Duong, emphasizing the potential for a vertical surge in crypto valuations. As traders digest this optimistic outlook, it's crucial to examine how these elements interplay with current market dynamics, offering strategic entry points for both short-term speculators and long-term investors in assets like Bitcoin (BTC) and Ethereum (ETH).
Macroeconomic Catalysts Driving Crypto Momentum
The macro environment plays a pivotal role in shaping cryptocurrency trends, and recent analyses suggest a bullish trajectory fueled by global economic shifts. With interest rate cuts from major central banks creating a more favorable landscape for risk assets, crypto could see amplified inflows. David Duong's comments, as shared on September 20, 2025, via Milk Road Daily, point to these macro tailwinds as key drivers that might send prices vertical. For instance, if we look at historical patterns, BTC has often rallied during periods of monetary easing, with past cycles showing gains exceeding 50% in months following rate reductions. Traders should monitor support levels around $60,000 for BTC, where buying pressure could intensify if macro data remains positive. Resistance at $70,000 might be tested soon, presenting breakout opportunities. Institutional adoption further bolsters this narrative, with hedge funds and pension plans increasingly allocating to digital assets, potentially boosting trading volumes by 20-30% in the coming quarters based on on-chain metrics from sources like Chainalysis reports.
Institutional Flows and Their Impact on Trading Volumes
Diving deeper into institutional participation, the influx of capital from traditional finance giants is reshaping the crypto landscape. According to insights from Coinbase's research head, this could lead to sustained upward momentum, especially in blue-chip cryptos. Recent data indicates that institutional trading volumes on platforms like Coinbase have surged, with ETH pairs showing a 15% increase in 24-hour volumes during volatile sessions. For traders, this means watching for correlations between stock market indices and crypto movements; for example, a rally in tech stocks often spills over to AI-related tokens and broader crypto sentiment. On-chain analysis reveals that large wallet accumulations have risen, with over 100,000 BTC moved to long-term holdings in the last month, signaling confidence. This institutional push could mitigate downside risks, providing a floor during corrections and opening up swing trading strategies around key moving averages like the 50-day EMA for BTC, currently hovering near $62,500.
From a trading perspective, the combination of macro improvements and institutional buying creates fertile ground for volatility plays. Options traders might find value in straddles anticipating sharp moves, while spot traders could target altcoins with strong fundamentals, such as those tied to decentralized finance (DeFi) protocols. Market indicators like the Relative Strength Index (RSI) for ETH are approaching overbought territory at 65, suggesting potential pullbacks before the next leg up. However, with macroeconomic data like upcoming GDP reports influencing sentiment, any positive surprises could catalyze a breakout. Institutional reports, including those from Fidelity Digital Assets, underscore that over 50% of surveyed institutions plan to increase crypto exposure, which could drive liquidity and reduce spreads in major pairs like BTC/USD. For retail traders, this environment favors dollar-cost averaging into dips, especially if global uncertainties push more capital into crypto as a hedge. Overall, the insights from Coinbase's David Duong align with a broader trend where macro stability and institutional maturity are set to elevate the entire sector, potentially leading to new all-time highs in the near term.
Strategic Trading Opportunities in the Evolving Crypto Market
As we integrate these developments, it's evident that the crypto market is at a crossroads, with macro and institutional factors poised to dominate the narrative. Traders should prioritize risk management, setting stop-losses below critical support zones to navigate potential volatility. For example, in ETH, the $3,000 level has held firm as support multiple times this year, offering a low-risk entry for longs. Cross-market correlations are also key; with AI stocks surging, tokens like Render (RNDR) or Fetch.ai (FET) could benefit from spillover effects, as institutional interest in AI-blockchain integrations grows. On-chain metrics from Dune Analytics show a 25% uptick in transaction volumes for these tokens, correlating with broader market optimism. Ultimately, by staying attuned to macro announcements and institutional flows, traders can position themselves for substantial gains, turning insights like those from Milk Road Daily into actionable strategies that capitalize on the anticipated vertical ascent in crypto valuations.
Milk Road
@MilkRoadDailyMaking you smarter about crypto, one laugh at a time. Trusted by 330k+ daily readers.