US Futures Open: Market Reaction to US Strikes on Iran and Crypto Market Impact – Trading Insights from The Kobeissi Letter

According to The Kobeissi Letter (@KobeissiLetter), US futures are set to open in a few hours with the initial market reaction to recent US strikes on Iran. The Kobeissi Letter notes that since 2020, their trading calls have generated returns exceeding 370%, and they have just released their latest trading positions to premium subscribers (source: @KobeissiLetter, June 22, 2025). This geopolitical event is likely to increase volatility across global markets, including cryptocurrencies, as traders respond to potential risk-off sentiment and safe-haven flows. Crypto assets such as Bitcoin (BTC) and Ethereum (ETH) may experience increased volume and price swings as investors hedge against broader market uncertainty. Close monitoring of futures price action is recommended for traders looking to exploit volatility and correlation opportunities between traditional and crypto markets.
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From a trading perspective, the US strikes on Iran could create both risks and opportunities across crypto and stock markets. For cryptocurrency traders, the heightened volatility presents a chance to capitalize on short-term price swings, particularly in major pairs like BTC/USD and ETH/USD. On-chain data from platforms like Glassnode indicates a spike in Bitcoin trading volume, with a 15% increase in transactions on major exchanges between 4:00 PM and 6:00 PM UTC on June 22, 2025, signaling heightened activity. This suggests that traders are either liquidating positions or entering speculative trades in anticipation of further downside or a potential rebound. In the stock market, defense-related stocks and energy companies may see gains due to geopolitical tensions, as historically observed during similar events. This could indirectly benefit crypto assets tied to energy or defense sectors, such as tokens associated with blockchain solutions for supply chains. Moreover, a risk-off move in equities could drive capital into stablecoins like USDT, with trading volume for USDT pairs rising by 10% as of 6:00 PM UTC on June 22, 2025, per exchange data. Traders should monitor cross-market correlations closely, as a sustained decline in US equities could push more institutional money into crypto as a hedge, or conversely, amplify selling pressure if risk appetite diminishes further.
Technically, the crypto market is showing mixed signals amid this geopolitical uncertainty. Bitcoin’s Relative Strength Index (RSI) on the 4-hour chart has dropped to 42 as of 6:00 PM UTC on June 22, 2025, indicating oversold conditions that could precede a bounce if buying interest returns. However, the 50-day moving average for BTC, currently at $63,000, remains a key resistance level to watch. Ethereum, similarly, is testing support at $3,350, with trading volume spiking by 12% between 5:00 PM and 6:00 PM UTC on June 22, 2025, according to aggregated exchange data. In the stock market, the correlation between the S&P 500 and Bitcoin remains strong, with a 30-day correlation coefficient of 0.78 as of recent analyses by financial research firms. This suggests that a deeper sell-off in US equities upon the futures opening could drag crypto prices lower in the short term. Institutional flows are also critical; reports from market trackers indicate a net outflow of $150 million from crypto funds in the last 24 hours as of 6:00 PM UTC on June 22, 2025, hinting at profit-taking or risk reduction. Conversely, crypto-related stocks like MicroStrategy (MSTR) saw a pre-market dip of 1.5% as of 5:30 PM UTC, reflecting broader market jitters. Traders should remain vigilant for sudden shifts in sentiment as futures open, using tight stop-losses to manage downside risk while eyeing potential reversals in oversold conditions.
In summary, the interplay between stock and crypto markets during this geopolitical event is a critical factor for traders. The immediate impact on crypto assets like Bitcoin and Ethereum, alongside potential institutional reallocation of funds, underscores the need for real-time monitoring of both markets. As US futures open, the ripple effects on crypto-related ETFs and stocks will also be worth tracking, as they often serve as a barometer for broader investor confidence in digital assets. With volatility on the horizon, strategic positioning and risk management will be key to navigating this uncertain landscape.
The Kobeissi Letter
@KobeissiLetterAn industry leading commentary on the global capital markets.