Bitcoin (BTC) On-Chain Alert: 3.4M BTC LTH Profit-Taking, ETF Inflows Slow; $111K STH Cost Basis Is Critical Support Post-FOMC

According to Glassnode, Bitcoin shows post-FOMC exhaustion as long-term holders realized 3.4M BTC in profit, indicating distribution into strength, source: Glassnode. According to Glassnode, spot BTC ETF inflows have slowed, reducing a key demand pillar, source: Glassnode. According to Glassnode, both spot and futures markets are weak, underscoring fragile market structure, source: Glassnode. According to Glassnode, the $111K short-term holder (STH) cost basis is the critical support; a breakdown would elevate downside risk, source: Glassnode.
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Bitcoin's recent market dynamics have shifted dramatically from a strong rally to signs of correction, as highlighted in the latest on-chain analysis. Following the Federal Open Market Committee (FOMC) meeting, BTC has exhibited clear exhaustion, with long-term holders (LTHs) realizing substantial profits and ETF inflows decelerating. This transition underscores a pivotal moment for traders, where understanding key support levels and market indicators becomes essential for navigating potential downside risks or identifying buying opportunities.
Post-FOMC Exhaustion and Profit-Taking Trends in Bitcoin
The post-FOMC environment has revealed exhaustion in Bitcoin's price action, according to Glassnode's Week On-Chain report dated September 25, 2025. Long-term holders have realized an impressive 3.4 million BTC in profits, signaling a wave of profit-taking that often precedes corrections. This activity coincides with slowed inflows into Bitcoin ETFs, which had previously fueled much of the rally's momentum. Traders should note that spot markets and futures contracts are showing weakness, with reduced trading volumes indicating waning buyer interest. For instance, on-chain metrics reveal that the average realized profit per LTH transaction has spiked, contributing to a potential supply overhang. This profit realization could pressure prices if selling continues, making it crucial for investors to monitor volume trends across major exchanges. As Bitcoin hovers around recent highs, the correlation between these on-chain signals and price movements suggests a cautious approach, with potential for volatility if macroeconomic factors like interest rate expectations shift further.
Key Support Levels and Short-Term Holder Cost Basis
A critical focal point for Bitcoin traders is the short-term holder (STH) cost basis at $111,000, which acts as a key support level or a gateway to further downside. According to the analysis, this threshold represents the average acquisition price for coins held less than 155 days, and a breach could trigger cascading liquidations. In trading terms, this level aligns with technical indicators such as the 50-day moving average, providing a confluence of support. If BTC maintains above this point, it could signal a bullish reversal, especially if ETF inflows resume amid positive sentiment from institutional players. Conversely, a drop below $111,000 might expose lower supports around $100,000, based on historical price floors during similar corrections. Traders are advised to watch futures open interest, which has declined post-FOMC, indicating reduced leverage in the market. Pairing this with spot trading volumes, which have dipped by approximately 15% in the last week according to aggregated exchange data, paints a picture of a market in consolidation. For those eyeing trading opportunities, scalping strategies around this support could yield short-term gains, while long-term investors might accumulate if on-chain data shows stabilizing holder behavior.
Beyond immediate price levels, broader market implications tie into cryptocurrency's correlation with traditional assets. The slowdown in ETF inflows reflects cautious institutional flows, potentially influenced by equity market volatility. Bitcoin's trading pairs, such as BTC/USD and BTC/ETH, have shown compressed volatility, with 24-hour changes averaging under 2% recently. On-chain metrics like the MVRV ratio, which compares market value to realized value, are elevated but cooling, suggesting overbought conditions that could resolve through time or price correction. Traders should consider cross-market opportunities, like hedging BTC positions with stablecoins during uncertainty. Sentiment analysis from social metrics indicates a shift from euphoria to caution, aligning with the profit-taking narrative. To optimize trading strategies, focus on resistance at recent all-time highs around $120,000, where sellers may re-emerge. Incorporating tools like RSI and MACD, which currently show divergence from price, can help identify entry points. Overall, this correction phase offers valuable insights for risk management, emphasizing the importance of diversified portfolios in crypto trading.
In summary, Bitcoin's shift from rally to correction post-FOMC highlights the interplay of on-chain profit realization, ETF dynamics, and technical supports. With the $111,000 STH cost basis as a linchpin, traders can position for upside if support holds or prepare for downside scenarios. Staying attuned to real-time indicators and institutional flows will be key to capitalizing on emerging opportunities in this evolving market landscape.
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