According to @LexSokolin, effective DeFi trading hinges on four machine-executable tasks—calculating impermanent loss, navigating numerous cross-chain bridges, optimizing gas, and monitoring liquidation ratios 24/7—capabilities that algorithms execute in milliseconds, not humans (source: @LexSokolin on X, Nov 21, 2025). The post signals that alpha in DeFi accrues to automated strategies and risk-management bots over manual retail execution, directly impacting liquidity provisioning, cross-chain arbitrage, and collateralized lending tactics (source: @LexSokolin on X, Nov 21, 2025). To remain competitive, traders should prioritize automation for LP impermanent-loss modeling, bridge-aware routing, gas-efficient order flow, and real-time collateral alerts in on-chain markets (source: @LexSokolin on X, Nov 21, 2025).